what's the best thing to do? I'm 78 atm been doing shifters, nebulas and chaotic clouds, I went upstairs to third floor and started to siph blood esswraiths and blood pools and skulls, also jumpers, but I seem to be failing a lot, what's the best thing to do for maximum xp?

Any nodes you can do above and including chaotic clouds are worth it over any esshounds/wraiths.

 

At 78 its better to give the yellow wizard the type of rune he requests as you get more xp than your highest rune.

 

Don't bother with blood wraiths after you get 30 blood runes, they'll be slow as hell. I believe the best hound/wraith at your level is law.