I'm not great with HiJack this, so I can't answer your problem, but if you are willing to spend money and are worried, the best really is ZoneAlarm (not the free version - most of the others). It will auto-start when windows runs and is very hard to stop unless the user absolutely agrees. It can detect programs attempting to do things like block the task manager, run other programs, change the registry, duplicate itself, close programs, set itself to auto-run and much more. It will then pop-up a confirmation dialouge where you can choose whether you want to allow it. If you choose no, I can almost guaratee it will stop whatever is causing the problem. Its great.