To what I know its almost impossible to alch without a loss, and I dont know any good items, but you can do other things while alching to minimise losses/profit. 1. Have a magpie familiar, it will forage gems which means free cash, its not much, but if you can find a good item to alch you'll lose barely anything 2. Do farming runs <--- unless you really hate farming do this every 1 and half hours or so 3. Alch and telegrab zammy wines - just go to the chaos temple, zammy wines sell 3k each and you'll probably alch about 5-6 times in between each telegrab so you can do the the math Or you can do two/all of the above to hopefully make a profit while alching