My stats aren't as good as you are and I haven't got the drakan's medallion. But I've been having succes with this setup: I don't know about higher-lvl'd options; But I bring food and just run back up after a chest, I can keep this up for quite a while, I don't use prayer. When my food's up I teleport to house, if you're more sure of urself u can just bring a charged glory amulet and take some extra food. Either Ancients & Ice blitz or Normal with Snare & polypore. Melee brothers: Polypore staff, ahrim skirt, robe & hood ice blitz, just freeze & run. Try to time stuns between the freeze. With Normal I click the target arrow before I hit the chest, immediately target him and snare (use snare on a keybind), with a little luck they're dead in one snare (40seconds). Just started using the Escape ability, melee brothers no longer hit me now. click (auto-attk blitz), escape, spam abilities until treshold, by this time they're out of snare, I can either stun them or use Surge to teleport over & behind them. Karil: Barrow melee chest & legs & Saradomin sword (however an equal or better stab weapon is better, karil's weak to stab) Karil is the most dangerous for me, followed by dharok. Ahrim: Ahrim set and crystal bow It takes a little longer without range gear, but ahrim hardly ever hits me. Inv full of sharks, maybe rocktails better for you. I don't use prayer. tips: with using teleport & preparation I try to stay in combat if im high health, to preserve my adrenaline. When I need to heal I use regeneration. Sometimes I don't use a shark in 2 or 3 runs, you'll do even better. This is but a theory but I think the barrow brothers get stronger when you pray against them. Which would make sense, there's a whole anti-prayer vibe in barrows, with the prayer drain & all. Don't be a nab and melee everything like you used to. I've seen lvl 200's die to dharok, like an hour ago infact. edit: just used blitzing after trying snaring, I found blitzing more efficient.