Technically the most ideal situation is that you have both the Nex sets and PoP sets for each combat style. Bosses to melee include: Bandos, Zamorak, and Saradomin Godwars Dungeons; Araxxor; Vorago (Base Tanking), Corporeal Beast; and Queen Black Dragon. Bosses to mage include: Zamorak, Armadyl, and Saradomin Godwars Dungeons; Vorago (any role); Rise of the Six Bosses to range include: Armadyl Godwars Dungeon, Vorago (dps), Rise of the Six, Araxxor, Queen Black Dragon, and Legiones Bosses requiring multiple styles: Nex, Kalaphite King, Dagannoth Kings If there is a boss that I didn't mention, it means that it isn't worth your time doing.