Are you reffering to combination runes (mist, lava, mud, smoke, etc.) when you say member runes? Most peope don't use those very often, except for the few quests when you need them. The tip.it guide has an explanation on how to make them though. Basically... You have to go to one of the altars (like air or water if you're making mist), bring some rune essence, the other rune type and a talisman of that. You'll use the talisman, the other runes and rune essence in the process. It fails quite often, so you won't get back the exact amount of runes that you expect. An amulet of binding (enchanted emerald necklace) gives 100% binding.