Hold off on the "first big sci-fi" line there. 2001, Planet of the Apes, Invasion of the Body Snatchers (1956!!), 1953 War of the Worlds, Solaris, Alien, Star Wars, THX 1138 just to name a few that predate Blade Runner. Blade Runner is one of my all-time favorite films Film noir mixed with Sci Fi in a meditation on what it is to be a human? Talk about a film-gasm. Plus a YOUNG Rutger Hauer--the "time to die" monologue he has at the end was a complete deviation from the original script and one of the most beautiful moments in cinema history. I thought the music was perfect, but I'm a sucker for synth music in film--though I never used to be. Anything in David Lynch or John Carpenter films is almost a guaranteed synth fest. Blade Runner 2 with the original crew is in the works, and they have publicly asked Harrison Ford to star again. With him returning to his role in the upcoming Star Wars film, it's possible he might agree to return as the one and only Deckard.