Perhaps not 48 hours, but I've been awake for 2 days with only 1 hour sleep and felt absolutely fine both days. I don't do drugs because mommy says drugs are bad and I'm a good boy, and stimulants mommy said are only for adults. Granted, the first night was my high school Grad Night, so I wasn't staring in front of a computer screen but rather out and about doing all kinds of activities we shall keep off the record. However, that's not to say that playing video games WON'T be a substitute. Not taking sides here, just thought I'd let you know that in special cases you can go 48 hours in minimal sleep and feel absolutely fine. Btw right after those 2 days I jumped straight into a normal sleep schedule without any additional feelings of fatigue. Shit was weird, I agree.