get a friend to block the bosses / find places to block them on your own and you will be fine. kamil might be a bit hard, just fire bolt with chaos gaunts and restore when your mage is low
the only one on there ive played and thought was good was metal gear 3. even after its been out for so long its my fav game, i wish i could play 1 2 and 4 to see what happens next in the story as watching them on utube isnt as good
the ones in the lighthouse are not very strong you could go there with 40 def and full rune and not get hit much so with 80 def full rune should be fine