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Breakthrough: Israel Develops Cancer Vaccine


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#1
The_Gabe
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http://unitedwithisr...cancer-vaccine/

As the world’s population lives longer than ever, if we don’t succumb to heart disease, strokes or accidents, it is more likely that cancer will get us one way or another. Cancer is tough to fight, as the body learns how to outsmart medical approaches that often kill normal cells while targeting the malignant ones.

In a breakthrough development, the Israeli company Vaxil BioTherapeutics has formulated a therapeutic cancer vaccine, now in clinical trials at Hadassah University Medical Center in Jerusalem. If all goes well, the vaccine could be available about six years down the road, to administer on a regular basis not only to help treat cancer but in order to keep the disease from recurring.
The vaccine is being tested against a type of blood cancer called multiple myeloma. If the substance works as hoped — and it looks like all arrows are pointing that way — its platform technology VaxHit could be applied to 90 percent of all known cancers, including prostate and breast cancer, solid and non-solid tumors.
“In cancer, the body knows something is not quite right but the immune system doesn’t know how to protect itself against the tumor like it does against an infection or virus. This is because cancer cells are the body’s own cells gone wrong,” says Julian Levy, the company’s CFO. “Coupled with that, a cancer patient has a depressed immune system, caused both by the illness and by the treatment.”
The trick is to activate a compromised immune system to mobilize against the threat.
A vaccine that works like a drug

A traditional vaccine helps the body’s immune system fend off foreign invaders such as bacteria or viruses, and is administered to people who have not yet had the ailment. Therapeutic vaccines, like the one Vaxil has developed, are given to sick people, and work more like a drug.

Vaxil’s lead product, ImMucin, activates the immune system by “training” T-cells –– the immune cells that protect the body by searching out and destroying cells that display a specific molecule (or marker) called MUC1. MUC1 is typically found only on cancer cells and not on healthy cells. The T-cells don’t attack any cells without MUC1, meaning there are no side effects unlike traditional cancer treatments. More than 90% of different cancers have MUC1 on their cells, which indicates the potential for this vaccine.

“It’s a really big thing,” says Levy, a biotechnology entrepreneur who was formerly CEO for Biokine Therapeutics. “If you give chemo, apart from the really nasty side effects, what often happens is that cancer becomes immune [to it]. The tumor likes to mutate and develops an ability to hide from the treatment. Our vaccines are also designed to overcome that problem.”

For cancers in an advanced stage, treatments like chemo or surgery to remove a large tumor will still be needed, but if the cancer can be brought down to scale, the body is then able to deal with it, Levy explains. ImMucin is foreseen as a long-term strategy — a shot every few months, with no side effects — to stop the cancer from reoccurring after initial treatments, by ensuring that the patient’s own immune system keeps it under control.

In parallel, the company is also working on a vaccine that treats tuberculosis, a disease that’s increasing worldwide, including in the developed world, and for which the current vaccine is often ineffective and treatment is problematic.

Based in Ness Ziona, Vaxil was founded in 2006 by Dr. Lior Carmon, a biotechnology entrepreneur with a doctorate in immunology from the Weizmann Institute of Science in

Rehovot. In June, Vaxil signed a memorandum of understanding to merge its activities into Sheldonco, a company traded on the Tel Aviv Stock Exchange.
By Rivka Borochov


Thought this was interesting.
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#2
Giordano
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Israel made it?


It's gonna cost millions of dollars even at supply-demand equilibrium.
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#3
Dheginsea
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Well nicely done Israel, also @ Giordano, I don't see it costing millions of dollars I think it'll be in high hundreds of thousands.
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#4
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I doubt its effectiveness, but hopefully it will work. Only time will tell with things like these.

#5
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Dag. This looks very promising. A treatment that doesn't involve radiation, months of recuperation, hair loss, ect...

Looks like it might be time to buy stock in Sheldonco.

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#6
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It's gonna cost millions of dollars even at supply-demand equilibrium.


I'm not really sure if it was the point you were trying to make, but it would've cost that much anywhere. Treatments aren't the cash cow that they used to be, not when insurances are declining to cover it because of cost.

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#7
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Interesting, but I am still skeptical. I still have some hopes.

#8
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>>see thread about Isreal
>>think of Gabe
>>look at OP
>>Gabe

I'm against this science btw. I'm alright with curing and treating disease and whatnot, but I see cancer as nature's way of saying YOU'RE DONE ON THIS PLANET NOW, MAKE ROOM FOR OTHERS. We're overpopulated as it is. The [formally?] incurable disease, plus homosexuality was nature's counter to the stranglehold humans have on it. I'm kind of disappointed in human welfare. If they're young and have cancer, sure fine go ahead. cure it away. But if you've lived a full life, cancer or some other way, I feel like after a while people just take up resources.

and no, I'm not trolling, anyone who played Hegemony with me could tell you this is the mentality I ran my country in lol

 

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#9
Giordano
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>>see thread about Isreal
>>think of Gabe
>>look at OP
>>Gabe

I'm against this science btw. I'm alright with curing and treating disease and whatnot, but I see cancer as nature's way of saying YOU'RE DONE ON THIS PLANET NOW, MAKE ROOM FOR OTHERS. We're overpopulated as it is. The [formally?] incurable disease, plus homosexuality was nature's counter to the stranglehold humans have on it. I'm kind of disappointed in human welfare. If they're young and have cancer, sure fine go ahead. cure it away. But if you've lived a full life, cancer or some other way, I feel like after a while people just take up resources.

and no, I'm not trolling, anyone who played Hegemony with me could tell you this is the mentality I ran my country in lol

Well that's absolutely terrible. :razz: Once the secret is known to the cure of cancer, it will be produced en masse. It's not like medicine take a lot of resources to make neither; it's just the demand that makes them so costly.

The issue on overpopulation is that it isn't a physical problem or even an resource supply problem, it's an efficency issue. If all farms in the world were as productive as Western farms and with even moderate infranstructure connecting it, world hunger will cease. But many farms still use manual work, yielding a very low amount. After that, it cannnot be stored and transported properly to markets - not to mention in poverished areas the consumers would have no money to buy it with. Do we hear about overpopulation issues in America or Europe? Hardly. Why? Because we have enough resources to fulfill us. We hear about overpopulation issues in China, India, and Africa, where most of the lower class is made up of literally peasants who use feet as their primary veichle of transportation on dirt roads to earn a couple of cents. Overpopulation is an efficiency issue, not a resources. We won't be wasting any more resources on cancer cures in Europe, because Africa won't be getting any of it anyway.

Also cancer is really a painful disease and I don't think you understand how painful it can be. My only personal experience I have with cancer is with my beloved pet dog, who had lymphatic cancer. He turned to be an energic dog quickly down to a sickly being who always laid down all day: he couldn't move much, he didn't eat anything, and would cry in pain at sudden movements. I can't imagine stomach cancer, skin cancer, or brain cancer being better off for anybody, animals or humans. The only blessing my dog received was he only endured this about two weeks before he died. Some people have cancer for months in this state.

Cancer is not a 'drop-dead the moment you get it' disease. It is one of the most disgusting acts of irony played out by nature. The common man does not need to be sacrificed to save resources; if anybody can solve the issue it is corporate entrepreneurs and politicians, not disease and disasters.



EDIT: My first post was a Jew joke, I'm sorry.
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#10
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I'm against this science btw. I'm alright with curing and treating disease and whatnot, but I see cancer as nature's way of saying YOU'RE DONE ON THIS PLANET NOW, MAKE ROOM FOR OTHERS. We're overpopulated as it is. The [formally?] incurable disease, plus homosexuality was nature's counter to the stranglehold humans have on it. I'm kind of disappointed in human welfare. If they're young and have cancer, sure fine go ahead. cure it away. But if you've lived a full life, cancer or some other way, I feel like after a while people just take up resources.


Please define a "full life" and "young". Back in the middle ages, 60 was old (full life?) but now, the life expectancey is someting like 78 years or so. You'd be telling everyone at 78 who gets cancer: Tough luck? Why don't you stop consuming resources yourself? If you are a kid (eg in school, college or university) you are consuming resources as well instead of generating them....

Also, al lot of former "incurable diseases" got eradicated. Should we bring them back for the sake of population control?

Back on-topic: I'm sceptic, but if this is what it looks like, this could be a great leap in cancer treatment.
But the fact that just one marker is targeted, looks like a down side for me. There are also tumors that do not express MUC-1. But even if it works "just" for multiple myeloma, it is good news for thousants of patients.


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#11
Atom Smash40
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I'm against this science btw. I'm alright with curing and treating disease and whatnot, but I see cancer as nature's way of saying YOU'RE DONE ON THIS PLANET NOW, MAKE ROOM FOR OTHERS. We're overpopulated as it is. The [formally?] incurable disease, plus homosexuality was nature's counter to the stranglehold humans have on it. I'm kind of disappointed in human welfare. If they're young and have cancer, sure fine go ahead. cure it away. But if you've lived a full life, cancer or some other way, I feel like after a while people just take up resources.

and no, I'm not trolling, anyone who played Hegemony with me could tell you this is the mentality I ran my country in lol


I agree to some extent. However, cancer is unbiased and often affects those who are perfectly fit by natural selection's standards.

Besides, has anyone seen I Am Legend? We aren't meant to cure cancer.

EDIT: My first post was a Jew joke, I'm sorry.


I got it LOL. I'm going to hell.

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#12
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I'm against this science btw. I'm alright with curing and treating disease and whatnot, but I see cancer as nature's way of saying YOU'RE DONE ON THIS PLANET NOW, MAKE ROOM FOR OTHERS. We're overpopulated as it is. The [formally?] incurable disease, plus homosexuality was nature's counter to the stranglehold humans have on it. I'm kind of disappointed in human welfare. If they're young and have cancer, sure fine go ahead. cure it away. But if you've lived a full life, cancer or some other way, I feel like after a while people just take up resources.

and no, I'm not trolling, anyone who played Hegemony with me could tell you this is the mentality I ran my country in lol


I agree to some extent. However, cancer is unbiased and often affects those who are perfectly fit by natural selection's standards.

Besides, has anyone seen I Am Legend? We aren't meant to cure cancer.

EDIT: My first post was a Jew joke, I'm sorry.


I got it LOL. I'm going to hell.


I'm so used to them that I detected it in a second :mellow:
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#13
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>>see thread about Isreal
>>think of Gabe
>>look at OP
>>Gabe

I'm against this science btw. I'm alright with curing and treating disease and whatnot, but I see cancer as nature's way of saying YOU'RE DONE ON THIS PLANET NOW, MAKE ROOM FOR OTHERS. We're overpopulated as it is. The [formally?] incurable disease, plus homosexuality was nature's counter to the stranglehold humans have on it. I'm kind of disappointed in human welfare. If they're young and have cancer, sure fine go ahead. cure it away. But if you've lived a full life, cancer or some other way, I feel like after a while people just take up resources.

and no, I'm not trolling, anyone who played Hegemony with me could tell you this is the mentality I ran my country in lol


Though I can see you're not trolling, I also see that you are speaking as a young person who is still very much coming to grips with the world, and has that sort of innocent (not to sound too patronising) amor fati that arises from having a happy, largely protected existence. In all likelihood, some experience of life proper will change your opinion on the matter. Or, as was the case with me, you may just realise it spontaneously.


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#14
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I'm so used to them that I detected it in a second :mellow:


same, lol. Why are there no jokes about other white creeds?


Though I can see you're not trolling, I also see that you are speaking as a young person who is still very much coming to grips with the world, and has that sort of innocent (not to sound too patronising) amor fati that arises from having a happy, largely protected existence. In all likelihood, some experience of life proper will change your opinion on the matter. Or, as was the case with me, you may just realise it spontaneously.


I've lead a sheltered life so to speak, lower middle class suburbia, good job, always get the essentials, yadda yadda, but I'm not immune to nature. My grandmother and my uncle both died of cancer within the past 12 years, my uncle only being 2 years ago. I loved them both, but they both lived their lives, lived laughed loved and whatnot. It was just their time.

I agree to some extent. However, cancer is unbiased and often affects those who are perfectly fit by natural selection's standards.

Besides, has anyone seen I Am Legend? We aren't meant to cure cancer.


I love that movie lol, and I don't see such a result as a complete impossibility either. Nature will conquer humanity. 99.99% of all species have been wiped from this earth. Humanity is no safer than the Dinosaurs, however more intelligent we may claim ourselves to be.

Please define a "full life" and "young". Back in the middle ages, 60 was old (full life?) but now, the life expectancey is someting like 78 years or so. You'd be telling everyone at 78 who gets cancer: Tough luck? Why don't you stop consuming resources yourself? If you are a kid (eg in school, college or university) you are consuming resources as well instead of generating them....

Also, al lot of former "incurable diseases" got eradicated. Should we bring them back for the sake of population control?


full life being accomplished, raised a family, contributed to society, that sort of thing. basically not being a waste of space their whole life, or had the chance to experience as much as possible. Young being too attatched to a youthly milestone to 'grow up' and experience full relationships, starting a family, having a job, owning property, that sort of thing. And bringing back former diseases is just silly, but notice how over time they've gotten worse? Polio, Small pox, Black Plague, all of these were bad, but let's be honest. Cancer is 'worse'. You can't prevent it. Everything causes it. There is literally nothing we can do about it [until recently apparently]. It's prolonged. It's painful. The only thing it isn't is contagious. I'd rather stop the evolution of disease at cancer before the next big human-killer comes around.

 

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#15
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As soon as one disease is cured, more will come to form. It's just one of nature's checks and balances on population.
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#16
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I never thought TIF was this cynical. Here we receive news that a cancer vaccine might hit markets in 6 years and suddenly it's all about man's mortality and the inevitable apocalypse.

Seriously guys, lighten up. We might be on the verge of curing [bleep]ing cancer here.

#17
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And bringing back former diseases is just silly, but notice how over time they've gotten worse? Polio, Small pox, Black Plague, all of these were bad, but let's be honest. Cancer is 'worse'. You can't prevent it. Everything causes it. There is literally nothing we can do about it [until recently apparently]. It's prolonged. It's painful. The only thing it isn't is contagious. I'd rather stop the evolution of disease at cancer before the next big human-killer comes around.

That's a flawed way of looking at things because it's completely wrong. Just because we "stop" at cancer doesn't mean the evolutionary process of other viruses will play fair and stop too; it's completely stupid to think like that. Medicine is an eternal war between humans and nature and if we give up now it is as if medieval doctors gave up then: we would still conduct blood letting and amputations at every little infection.
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#18
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I've lead a sheltered life so to speak, lower middle class suburbia, good job, always get the essentials, yadda yadda, but I'm not immune to nature. My grandmother and my uncle both died of cancer within the past 12 years, my uncle only being 2 years ago. I loved them both, but they both lived their lives, lived laughed loved and whatnot. It was just their time.


So it's not really cancer that says "times up" but moreso whether the person in question has lived a fulfilling life yet? I used to be of the same opinion but thinking deeper on it, I would think giving up life would be one of the worst feelings ever. Imagine you are faced with the question to never see, feel, or experience anything ever again because all the people you fought so hard to give good lives to "want their turn".

I mean yeah... logically speaking, hooking a 90-year-old up to life support doesn't seem to be such a practical use of our resources, but I'm not going to pretend to know the mental pain they are facing and how much something like that would mean to them. As rude and dimwitted as I find most old people to be, I believe they deserve as long of a life as they can get.

same, lol. Why are there no jokes about other white creeds?


Canadians and French. Italians also get it pretty bad from Family Guy.

#19
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I've lead a sheltered life so to speak, lower middle class suburbia, good job, always get the essentials, yadda yadda, but I'm not immune to nature. My grandmother and my uncle both died of cancer within the past 12 years, my uncle only being 2 years ago. I loved them both, but they both lived their lives, lived laughed loved and whatnot. It was just their time.


So it's not really cancer that says "times up" but moreso whether the person in question has lived a fulfilling life yet? I used to be of the same opinion but thinking deeper on it, I would think giving up life would be one of the worst feelings ever. Imagine you are faced with the question to never see, feel, or experience anything ever again because all the people you fought so hard to give good lives to "want their turn".

I mean yeah... logically speaking, hooking a 90-year-old up to life support doesn't seem to be such a practical use of our resources, but I'm not going to pretend to know the mental pain they are facing and how much something like that would mean to them. As rude and dimwitted as I find most old people to be, I believe they deserve as long of a life as they can get.

same, lol. Why are there no jokes about other white creeds?


Canadians and French. Italians also get it pretty bad from Family Guy.


I don't think you understand what a creed is :P

And I believe this because I believe that everyday you should tell yourself tomorrow you won't ever see, feel, or experience anything ever again if that's what it takes to motivate you from day to day. Why waste your time when you only live once? Enjoy it. If you don't seize the opportunity, that's on you - why disregard your responsibility of enjoying yourself in this world and then drain the resources of those that still can? If I ever am diagnosed with cancer [semi-likely] I want it immediately removed via surgery. If not, I'll live my life like I've never lived before right to the very end. No life support for me.

 

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#20
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same, lol. Why are there no jokes about other white creeds?


Have you not heard any Catholic priest jokes?

on topic: I really do hope that this actually works and not in the I Am Legend style.
edit: woo 400 posts
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