My setup with maxed melee, 80 prayer and 92 magic: Gear: Verac Helm Verac Brassard Verac Plateskirt Amulet of Fury Wizard boots/Infinity Boots Barrows Gloves Trimmed Skillcape Black Salamander Harralander Tar I bring in my inventory: Four Prayer Potions (4) One spade Whip DDS Rune Defender House Teleport Tabs 17 Sharks 2 Salmon (extra food for the maze) First of all, I kill them in this order: Dharok (Pray+Black Sally) Karil (Pray+ DDS spec on slash/whip) Ahrim (Pray+Whip) If the first 3 are killed and I have prayer left I use it on the rest until I run out Verac (Black Sally) Guthan (Black Sally) Torag (Black Sally) My biggest tip for saving money on prayer potions is only sip after you know you're going to fight someone. In other words, if you have 2 prayer left, don't sip until after you've opened the tomb and started fighting. Although a small detail, unnecessary sips can really add up over time. This set up might not be the absolute best for you, but you can tweak it to fit your needs. This is what I've found best for me.