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http://news.yahoo.com/s/ap/20090424/ap_ ... _swine_flu

 

 

 

 

 

 

 

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MEXICO CITY Mexico shut down schools, museums, libraries and state-run theaters across its overcrowded capital Friday in hopes of containing a swine flu outbreak that authorities say killed at least 20 people and perhaps dozens more. World health authorities worried openly that the strange new virus could become a global epidemic.

 

 

 

The U.S. Centers for Disease Control and Prevention said tests show some of the Mexico victims died from the same new strain of swine flu that sickened eight people in Texas and California.

 

 

 

Mexico put the confirmed toll at 20 dead, but 40 other fatalities were being probed, and at least 943 nationwide were sick from the suspected flu, the health department said.

 

 

 

Scientists said the virus combines genetic material from pigs, birds and humans in a way researchers have not seen before.

 

 

 

"We are very, very concerned," spokesman Thomas Abraham said.

 

 

 

"We have what appears to be a novel virus and it has spread from human to human," he said. "It's all hands on deck at the moment."

 

 

 

President Felipe Calderon cancelled a trip and met with his Cabinet to coordinate Mexico's response.

 

 

 

The government planned to administer its remaining 500,000 vaccines from the flu season to health workers, the highest risk group, although it is not known how effective they are on swine flu. It said it also has enough oseltamivir, the generic name of Tamiflu, to treat 1 million people, but the medicine will be strictly controlled and handed out only by doctors.

 

 

 

The CDC says Tamiflu and Relenza do seem effective against the new strain. Roche, the maker of Tamiflu, said the company is prepared to immediately deploy a stockpile of the drug if requested. Both drugs must be taken early, within a few days of the onset of symptoms, to be most effective.

 

 

 

Authorities urged people to avoid hospitals unless they had a medical emergency, since hospitals are centers of infection.

 

 

 

They also said Mexicans should refrain from customary greetings such as shaking hands or kissing cheeks, and authorities at Mexico City's international airport were questioning passengers to try to prevent anybody with possible influenza from boarding airplanes and spreading the disease.

 

 

 

But the CDC said Americans need not avoid traveling to Mexico, as long as they take the usual precautions, such as frequent handwashing.

 

 

 

"We certainly have 60 deaths that we can't be sure are from the same virus, but it is probable," said Health Secretary Jose Cordova. He called it a "new, different strain ... that originally came from pigs."

 

 

 

Epidemiologists are particularly concerned because the only people killed so far were normally less-vulnerable young people and adults. It's possible that more vulnerable populations infants and the aged had been vaccinated against other strains, and that those vaccines may be providing some protection.

 

 

 

All eight of the California and Texas residents recovered from symptoms that were like those of the regular flu, mostly involving fever, cough and sore throat, though some of the seven also experienced vomiting and diarrhea.

 

 

 

Scientists have long been concerned that a new flu virus could launch a pandemic, a worldwide spread of a killer disease. A new virus could evolve when different flu viruses infect a pig, a person or a bird, mingling their genetic material. The resulting hybrid could spread quickly because people would have no natural defenses against it.

 

 

 

The most notorious flu pandemic is thought to have killed at least 40 million people worldwide in 1918-19. Two other, less deadly flu pandemics struck in 1957 and 1968.

 

 

 

Nobody can predict when pandemics will happen. Scientists had been concerned about swine flu in 1976, for example, and some 40 million Americans were vaccinated. No flu pandemic ever appeared, but thousands of vaccinated people filed claims saying they'd suffered a paralyzing condition andother side effects from the shots.

 

 

 

In recent years, scientists have been particularly concerned about birds. There have been deaths from bird flu, mostly in Asia, but the virus has so far been unable to spread from person to person easily enough to touch off a pandemic.

 

 

 

Closing the schools across the metropolis of 20 million kept 6.1 million students home from day care centers through high schools, and thousands more were affected as colleges and universities closed down. Parents scrambled to juggle work and family concerns due to what local media said was the first citywide schools closure since Mexico City's devastating 1985 earthquake.

 

 

 

Authorities also advised capital residents not to go to work if they felt ill, and to wear surgical masks if they had to move through crowds. A wider shutdown perhaps including shutting down government offices was being considered.

 

 

 

"It is very likely that classes will be suspended for several days," Cordova said. "We will have to evaluate, and let's hope this doesn't happen, the need to restrict activity at workplaces."

 

 

 

Mexico's initial response in its overcrowded capital brought to mind other major outbreaks such as when SARS hit Asia. At its peak in 2003, Beijing was the hardest-hit city in the world. Schools, cinemas and restaurants were shuttered to prevent the spread the deadly respiratory virus, and thousands of people were quarantined at home.

 

 

 

In March 2008, Hong Kong ordered more than a half million young students to stay home for two weeks because of a flu outbreak. It was the first such closure in Hong Kong since the outbreak of SARS, or severe acute respiratory syndrome.

 

 

 

Lillian Molina and other teachers at the Montessori's World preschool scrubbed down their empty classrooms with Clorox, soap and Lysol on Friday between fielding calls from worried parents. While the school has had no known cases among its students, Molina supported the government's decision to shutter classes, especially in preschools.

 

 

 

"It's great they are taking precautions," she said. "I think it's a really good idea."

 

 

 

Still, U.S. health officials said it's not yet a reason for alarm in the United States. The five in California and two in Texas have all recovered, and testing indicates some common antiviral medications seem to work against the virus.

 

 

 

Schuchat of the CDC said officials believe the new strain can spread human-to-human, which is unusual for a swine flu virus. The CDC is checking people who have been in contact with the seven confirmed U.S. cases, who all became ill between late March and mid-April.

 

 

 

The U.S. cases are a growing medical mystery because it's unclear how they caught the virus. The CDC said none of the seven people were in contact with pigs, which is how people usually catch swine flu. And only a few were in contact with each other.

 

 

 

CDC officials described the virus as having a unique combination of gene segments not seen in people or pigs before. The bug contains human virus, avian virus from North America and pig viruses from North America, Europe and Asia.

 

 

 

Health officials have seen mixes of bird, pig and human virus before, but never such an intercontinental combination with more than one pig virus in the mix.

 

 

 

Scientists keep a close eye on flu viruses that emerge from pigs. The animals are considered particularly susceptible to both avian and human viruses and a likely place where the kind of genetic reassortment can take place that might lead to a new form of pandemic flu, said Dr. John Treanor, an infectious disease specialist at the University of Rochester Medical Center.

 

 

 

The virus may be something completely new, or it may have been around for a while but was only detected now because of improved lab testing and disease surveillance, CDC officials said.

 

 

 

The virus was first detected in two children in southern California a 10-year-old boy in San Diego County and a 9-year-old girl in neighboring Imperial County.

 

 

 

It's not known if the seasonal flu vaccine Americans got this winter protects against this type of virus. People should wash their hands and take other precautions, CDC officials said.

 

 

 

____

 

 

 

Associated Press Writers Maria Cheng in London, Traci Carl in Mexico City and Mike Stobbe in Atlanta, Georgia, contributed to this report.[/hide]

 

 

 

Understanding the outbreak: an influenza biology primer

 

http://arstechnica.com/science/news/200 ... primer.ars

 

 

 

Washington Posts Excellent Graphic Explaining the Flu Virus

 

http://www.washingtonpost.com/wp-dyn/co ... 00197.html

 

 

 

Swine flu: The predictable pandemic? [Discusses why our immune systems are not ready.]

 

http://www.newscientist.com/article/mg2 ... demic.html

 

 

 

 

 

Swine flu: more on the genetics of the virus

 

http://scienceblogs.com/effectmeasure/2 ... netics.php

 

 

 

Swine flu and deaths in healthy adults--cytokine storm? [Conclusion]

 

http://scienceblogs.com/aetiology/2009/ ... health.php

 

 

 

For updates concerning cases or discoveries concerning the viruss genetics, I recommend reading the blog Effect Measure from scienceblogs.com:

 

http://scienceblogs.com/effectmeasure/

 

 

 

 

 

thanks magekillr for links ::'

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It seems there are atleast 2 drugs effective in stopping the virus, so if it begins to infect more and more people we will be ready to destroy it.

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I call zombies

 

 

 

but yeah this could get fairly bad; as long as the drugs are effective I think we should be able to manage.

 

*Loads up shotguns, automatic weapons, and pisotls*

 

 

 

I need some gum...

"Let your anger be as a monkey in a piñata... hiding amongst the candy... hoping the kids don't break through with the stick." - Master Tang

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I call zombies

 

 

 

but yeah this could get fairly bad; as long as the drugs are effective I think we should be able to manage.

 

*Loads up shotguns, automatic weapons, and pisotls*

 

 

 

I need some gum...

 

Congratulations, of all the weapons you picked, only one would make any sense to use against zombies :thumbsup:

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I'm not sure how much it will spread because there's not much good information in that article. At least it seems that conventional antivirals might have some use here.

 

 

 

Flu outbreaks like this do sound a bit worrying, especially since there seems to be a bigger and badder strain every season.

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When i think virus I somehow think of a resident evil type of thing....MEXICAN ZOMBIES! They'll be playing in ther little bands with their sombreros and their limbs will be falling off...joyful =D>

 

 

 

And I call a sawn off shotgun toooo! :thumbsup:

 

 

 

But yeah; off my zombie spamming thingy; really bad craic when theres a viral outbreak >.< though they have them methods to help fight the virus; don't they? :?

 

And hopefully they kill the zombies quickly... 8-)

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Aw, how cute, Mexico thinks it can make a global pandemic. But we'll probably have some vaccine for this eventually, and if you don't eat pork you might be safe (though maybe not, I didn't read the whole thing).

 

 

 

And Drazhar, you're thinking of the leper colonies they have near all of the beaches.

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I hope President Felipe Cuaderno can do something about it! It's probably an evil plot by the drug cartels to take over the world.

SWAG

 

Mayn U wanna be like me but U can't be me cuz U ain't got ma swagga on.

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Swine flu? Pah, the government sure does come up with convincing names for these zombie pandemics!

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what i find odd is that it has the charecteristics of the avian, swine, and human strains all at once. this would be big trouble because it means that the virus has the potential to spread through birds and not just pigs and humans as in previouse strains.

 

 

 

this could get very bad.

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personally, i'd wait for a better article, this one can't keep it's facts straight.

 

The U.S. Centers for Disease Control and Prevention said tests show some of the Mexico victims died from the same new strain of swine flu that sickened eight people in Texas and California.

 

All eight of the California and Texas residents recovered from symptoms that were like those of the regular flu, mostly involving fever, cough and sore throat, though some of the seven also experienced vomiting and diarrhea.

 

Still, U.S. health officials said it's not yet a reason for alarm in the United States. The five in California and two in Texas have all recovered, and testing indicates some common antiviral medications seem to work against the virus.

 

The U.S. cases are a growing medical mystery because it's unclear how they caught the virus. The CDC said none of the seven people were in contact with pigs, which is how people usually catch swine flu. And only a few were in contact with each other.

 

 

 

so, what i gather, as those quotes are in order from the article, is that in the middle of quote #2, someone suddenly wasn't infected with the virus dropping the number to seven.

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Yea, no school today for me

 

 

 

wooohhh

 

 

 

 

 

They are giving us that vaccine thing on Monday morning (that is if it's not canceled)

 

My sincerest condolences to your country for not having succeeded in deporting you yet. Are you aware you are at a very serious health risk?

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You know what would be horrible? What if a fat person got the disease and died. Think of all the jokes that people would crack about the fat guy dying from swine flu.

SWAG

 

Mayn U wanna be like me but U can't be me cuz U ain't got ma swagga on.

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You know what would be horrible? What if a fat person got the disease and died. Think of all the jokes that people would crack about the fat guy dying from swine flu.

 

Or a cop.

 

 

 

EDIT: Crap! It's gotten in SA appearently. And 2 kids not far from my school are infected. I may die to a Mexican disease. :wall:

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It's a good thing I don't come in contact with many people living in the bush.. or is that a bad thing. My immune system may be frail.. :ohnoes:

 

 

 

Best of luck to the Mexicans.

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I call zombies

 

 

 

but yeah this could get fairly bad; as long as the drugs are effective I think we should be able to manage.

 

*Loads up shotguns, automatic weapons, and pisotls*

 

 

 

I need some gum...

 

Congratulations, of all the weapons you picked, only one would make any sense to use against zombies :thumbsup:

 

 

 

Well an automatic weapon with sufficient caliber and muzzle velocity (think along the lines of RPK-74 or similar) would cause huge damage that could kill a zombie probably pretty easily, assuming you get hits in the head. A powerful pistol with hollowpoints would also do pretty good damage, but with the similar limitation of the machine gun. And then there's special mercury bullets designed to transfer all momentum into the target, I'd probably call 'em headpoppers.

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Yea, no school today for me

 

 

 

wooohhh

 

 

 

 

 

They are giving us that vaccine thing on Monday morning (that is if it's not canceled)

 

My sincerest condolences to your country for not having succeeded in deporting you yet. Are you aware you are at a very serious health risk?

 

 

 

 

 

~~yeah~~

 

 

 

Why would i be deported? I am aware and life continues, it's not like ZZZOMG WE ARE DEAD!!!!OMGOGMOGM!!

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I call zombies

 

 

 

but yeah this could get fairly bad; as long as the drugs are effective I think we should be able to manage.

 

*Loads up shotguns, automatic weapons, and pisotls*

 

 

 

I need some gum...

 

Congratulations, of all the weapons you picked, only one would make any sense to use against zombies :thumbsup:

 

Automatic weapons and pistols are good against zombies if you know how to aim...

"Let your anger be as a monkey in a piñata... hiding amongst the candy... hoping the kids don't break through with the stick." - Master Tang

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